Thursday 25th April 2024

Decline in heart failure deaths has been undone, led by people under 45

Heart failure mortality rates are moving in the wrong direction, a new analysis reports, reversing a decline in deaths that means more people in the United States are dying of the condition today than 25 years ago. The concerning conclusion comes as newer medications are raising hopes for better outcomes in the years to come.

A research letter published Wednesday in JAMA Cardiology tracked U.S. death certificate data from 1999 through 2021, revealing a steady drop in deaths until 2012, when rates plateaued, then began to rise steadily, and accelerated upward once the Covid-19 pandemic arrived. Disparities between men and women and among racial and ethnic groups moved up almost in lockstep, but there was one glaring exception: age. 

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An Ex-DOD Hacker Raises $20 Million To Stop ChatGPT-Fueled Cyberattacks - Forbes (No paywall)

A cyber startup founded by an ex-Defense Department hacker announces a $20 million raise and a presidential candidate as a customer.

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Do You Know How to Spot Foods That Are Ultraprocessed?

Highly processed foods have been linked to depression, anxiety and cognitive decline, among other things. Test your knowledge of how to spot them.

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How Long Does It Take to Get Fit Again? (Published 2023)

We all stray from exercise sometimes. Here’s how your body will bounce back.

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Opinion | This Is What a Miracle Drug Looks Like. And It Only Costs $5 to Make.

The effects of semaglutide drugs won’t just be cosmetic

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Aristotle plus generosity: How to soften the hard-boiled leader

I was on a plane, the regular shuttle between Boston and Washington, DC, sitting next to Steve, who had been my mentor since the day I joined BCG (Boston Consulting Group). We were in the bulkhead seats, on the right side of the plane. Yes, I do recall this detail; it was a vivid moment for me. 

He and I were on our way to DC to house hunt and open BCG’s Washington, DC, office, an office that had been a year in the planning. He was a senior partner; I was a manager at the time. I had already moved my family to DC to start two of my children in school. Steve and his spouse were going to follow sometime in the fall. 

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The Universe might never run out of hydrogen

Nothing in this Universe lasts forever, no matter how large, massive, or enduring it appears to be. Every star that’s ever born will someday run out of fuel in its core and die. Every galaxy that’s actively forming stars will someday run out of star-forming material and cease doing so. And every light that shines will someday cool off and go dark. If we wait long enough, there will be nothing to see, observe, or even extract energy from; when it reaches a state of maximal entropy, the cosmos will achieve a “heat death,” the inevitable final-stage in our cosmic evolution.

But what, exactly, does that mean for the simplest atom of all: hydrogen, the most common element in the Universe since the start of the Big Bang? That’s what Bill Thomson wants to know, writing in to ask:

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"Cultures of growth": How small changes can build stronger, more successful teams

In 2011, software engineer and satirist Manu Cornet posted a cartoon on his blog mocking Microsoft’s culture of cutthroat competition under CEO Steve Ballmer. The cartoon depicted the company’s org chart as a collection of guns, each one pointing at another employee. It became a viral sensation.

Enter Satya Nadella. When Nadella became Microsoft’s CEO in 2014, he restructured the company’s culture around the psychological concept of a “growth mindset.” He built it into strategy decisions, resource allocations, and performance evaluations. He even revised the company’s mission statement to include “empower every person and every organization on the planet to achieve more.”

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Why a James Webb Space Telescope mystery doesn't (necessarily) break cosmology

On Christmas Day, 2021, an Ariane 5 rocket leaped from its launch pad in French Guiana. Perched on the rocket’s nose was the long-awaited James Webb Space Telescope (JWST). The JWST was designed to perform several tasks, but one of the most important was to study the first stars and galaxies to come into existence. The telescope has performed magnificently; however, some troubling observations have been reported.

When the JWST took its first look at the sky, it seemed to have found galaxies completely unexplained by accepted theory. Astronomers worried that our understanding of the Universe’s early moments was fatally flawed and cosmology broken. Some press reports even hinted that the Big Bang was wrong.

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Exploited, Let Down, and Unfazed: What Small-Business Owners Are Saying About the Foxtrot Fallout

LaVitola gave a generic response, citing ambitious expansion plans for what began as a digital-only corner store and grew into a high-end convenience chain that secured $100 million in Series C funding in 2022. But on Tuesday, April 23, those plans ended with the abrupt closure of 33 Foxtrot locations (and two locations of upscale grocery store Dom's Market, which merged with Foxtrot into Outfox Hospitality at the end of 2023) across multiple states. The job loss is more than 1,000, according to Eater Chicago.

The Foxtrot co-founder might have given an uninspiring answer to a basic question, but his explanation of the company's business model -- and the contrarian beliefs Foxtrot was built on -- provides more insight into the current crisis the company's closure has created among small-business owners.


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